瀬川グループ分子科学研究所

張本尚 (Takashi Harimoto)

分子科学研究所　生命・錯体分子科学研究領域　錯体物性研究部門　助教
ORCID iD icon https://orcid.org/0000-0002-0405-5506
Scopus Author ID: 57214099977
E-mail: t-harimoto [at] ims.ac.jp

学歴

2020年3月　北海道大学理学部化学科卒業 (鈴木孝紀教授)

2021年9月　北海道大学大学院総合化学院総合化学専攻修士課程修了 (鈴木孝紀教授)

2024年3月　北海道大学大学院総合化学院総合化学専攻博士課程修了博士(理学) (鈴木孝紀教授)

職歴

2022年4月~2024年3月　日本学術振興会特別研究員 (DC1)

2024年4月~現在　分子科学研究所生命・錯体分子科学研究領域錯体物性研究部門　助教

論文

17) Structural-Change-Induced Two-Stage Redox Behavior of Pentacenebisquinodimethane with Tricolor Chromism.
Y. Ishigaki, S. Mizuno, T. Harimoto, T. Shimajiri, T. Suzuki
Chem. Asian J. 2024, in press. [DOI: 10.1002/asia.202400316]

16) Domino-Redox Reaction Induced by An Electrochemically Triggered Conformational Change.
T. Harimoto, T. Tadokoro, S. Sugiyama, T. Suzuki, Y. Ishigaki
Angew. Chem. Int. Ed. 2024, 63, e202316753. [DOI: 10.1002/anie.202316753]
Highlighted in Chem-Station Spotlight Research No. 597

15) Carbon-based Biradicals: Structural and Magnetic Switching.
Y. Ishigaki, T. Harimoto, T. Shimajiri, T. Suzuki
Chem. Rev. 2023, 123, 13952-13965. [DOI: 10.1021/acs.chemrev.3c00376]

14) Synthesis and Functional Control of Near-infrared Electrochromic Molecules Based on Redox-active Para-quinodimethane Scaffolds.
T. Harimoto, Y. Ishigaki
J. Synth. Org. Chem. Jpn. 2023, 81, 963-977. [DOI: 10.5059/yukigoseikyokaishi.81.963]

13) Double Dynamic Structural Change Enabling Tricolor Chromism by the Realization of Apparent Two-Electron Transfer to Skip the Open-Shell State.
T. Harimoto, Y. Sugai, K. Sugawara, T. Suzuki, Y. Ishigaki
Chem. Eur. J. 2023, 29, e202301476. [DOI: 10.1002/chem.202301476]

12) One-Pot Synthesis of Helical Azaheptalene and Chiroptical Switching of an Isolable Radical Cation.
Y. Nishimura, T. Harimoto, T. Suzuki, Y. Ishigaki
Chem. Eur. J. 2023, 29, e202301759. [DOI: 10.1002/chem.202301759]
Preprint: ChemRxiv 2023 [DOI: 10.26434/chemrxiv-2023-sc6tf]

11) Enhancement of NIR-Absorbing Ability of Bis(diarylmethylium)-Type Dicationic Dyes Based on an Ortho-Substitution Strategy.
T. Harimoto, T. Suzuki, Y. Ishigaki
Chem. Eur. J. 2023, 29, e202203899. [DOI: 10.1002/chem.202203899]

10) Single-Molecule Observation of Redox Reactions Enabled by Rigid and Isolated Tripodal Molecules.
Y. Kobayashi, Y. Yokota, R. A. Wong, M. Hong, J. Takeya, S. Osawa, F. Ishiwari, Y. Shoji, T. Harimoto, K. Sugimoto, Y. Ishigaki, T. Suzuki, T. Fukushima, Y. Kim
J. Phys. Chem. C 2023, 127, 746-758. [DOI: 10.1021/acs.jpcc.2c07362]

9) Geometrical and Electronic Structure of Cation Radical Species of Tetraarylanthraquinodimethane: An Intermediate for Unique Electrochromic Behavior.
Y. Ishigaki, R. Fukagawa, K. Sugawara, T. Harimoto, T. Suzuki
Chem. Asian J. 2022, 17, e202200914. [DOI: 10.1002/asia.202200914]

8) A Ratiometric Photoacoustic Probe with a Reversible Response to Hydrogen Sulfide and Hydroxyl Radicals for Dynamic Imaging of Liver Inflammation.
L. Wu, W. Zeng, Y. Ishigaki, J. Zhang, H. Bai, T. Harimoto, T. Suzuki, D. Ye
Angew. Chem. Int. Ed. 2022, 61, e202209248. [DOI: 10.1002/anie.202209248]

7) Redox-Active Hydrocarbons: Isolation and Structural Determination of Cationic States toward Advanced Response Systems.
T. Harimoto, Y. Ishigaki
ChemPlusChem 2022, 87, e202200013. [DOI: 10.1002/cplu.202200013]

6) An Activatable Afterglow/MRI Bimodal Nanoprobe with Fast Response to H₂S for In Vivo Imaging of Acute Hepatitis.
W. Zeng, L. Wu, Y. Ishigaki, T. Harimoto, Y. Hu, Y. Sun, Y. Wang, T. Suzuki, H.-Y. Chen, D. Ye
Angew. Chem. Int. Ed. 2022, 61, e202111759. [DOI: 10.1002/anie.202111759]

5) Generation of hydroxyl radical-activatable ratiometric near-infrared bimodal probes for early monitoring of tumor response to therapy.
L. Wu,^# Y. Ishigaki,^# W. Zeng,^# T. Harimoto, B. Yin, Y. Chen, S. Liao, Y. Liu, Y. Sun, X. Zhang, Y. Liu, Y. Liang, P. Sun, T. Suzuki, G. Song, Q. Fan, D. Ye
Nat. Commun. 2021, 12, 6145. [DOI: 10.1038/s41467-021-26380-y (open access)]
^#These authors contributed equally.

4) Redox-active tetraaryldibenzoquinodimethanes.
Y. Ishigaki, K. Sugawara, T. Tadokoro, Y. Hayashi, T. Harimoto, T. Suzuki
Chem. Commun. 2021, 57, 7201-7214. [DOI: 10.1039/D1CC02260A]

3) Hysteretic Three-State Redox Interconversion among Zigzag Bisquinodimethanes with Non-fused Benzene Rings and Twisted Tetra-/Dications with [5]/[3]Acenes Exhibiting Near-Infrared Absorptions.
Y. Ishigaki, T. Harimoto, K. Sugawara, T. Suzuki
J. Am. Chem. Soc. 2021, 143, 3306-3311. [DOI: 10.1021/jacs.1c00189]
• Highlighted in Chem-Station Spotlight Research No. 308

2) Hexaarylbutadiene: A Versatile Scaffold with Tunable Redox Properties towards Organic Near-Infrared Electrochromic Material.
Y. Ishigaki, T. Harimoto, K. Sugimoto, L. Wu, W. Zeng, D. Ye, T. Suzuki
Chem. Asian J. 2020, 15, 1147-1155. [DOI: 10.1002/asia.201901816]

1) H₂S-activatable near-infrared afterglow luminescent probes for sensitive molecular imaging in vivo.
L. Wu,^# Y. Ishigaki,^# Y. Hu, K. Sugimoto, W. Zeng, T. Harimoto, Y. Sun, J. He, T. Suzuki, X. Jiang, H.-Y. Chen, D. Ye
Nat. Commun. 2020, 11, 446. [DOI: 10.1038/s41467-020-14307-y (open access)]
^#These authors contributed equally.

受賞

2019 年 9 月第 30 回基礎有機化学討論会『ポスター賞』

2020 年 3 月 2019(令和元)年度『北海道大学理学部同窓会賞』

2021 年 4 月公益財団法人戸部眞紀財団奨学生に採択

2021 年 6 月第 33 回万有札幌シンポジウム『Best ポスター賞』

2021 年 9 月第 31 回基礎有機化学討論会『ポスター賞』

2022 年 8 月第 53 回構造有機化学若手の会『ポスター賞』

2022 年 9 月第 32 回基礎有機化学討論会『ポスター賞』

2022 年 10 月『第 13 回大津会議アワードフェロー』に採択

2022 年 11 月第 2 回基礎有機化学会若手オンラインシンポジウム『優秀ディスカッション賞』

2024年 3 月日本化学会第 104春季年会(2024)『学生講演賞』